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Accueil > Axes de recherche > Mécanismes physiopathologiques et régulation thérapeutique des réponses auto-immunes (H. Dumortier)

Publications 2011-2019

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Murera D, Malaganahalli S, Martin C, Reina G, Fauny JD, Dumortier H, Vasquez E, Bianco A (2019) Few layer graphene does not affect the function and the autophagic activity of primary lymphocytes. Nanoscale 30, 10493-10503.

Sawaf M, Fauny JD, Felten R, Sagez F, Gottenberg JE, Dumortier H, Monneaux F (2018) Defective BTLA functionality is rescued by restoring lipid metabolism in lupus CD4+ T cells from lupus patients. JCI Insight. 3, e99711.

Mercer LK, Askling J, Raaschou P, Dixon WG, Dreyer L, Hetland ML, Strangfeld A, Zink A, Mariette X, Finckh A, Canhao H, Iannone F, Zavada J, Morel J, Gottenberg JE, Hyrich KL, Listing J (2017) Risk of invasive melanoma in patients with rheumatoid arthritis treated with biologics : results from a collaborative project of 11 European biologic registers. Ann Rheum Dis. 76, 386-391.

Gies V, Wagner A, Seifert C, Guffroy A, Fauny JD, Knapp AM, Pasquali JL, Martin T, Dumortier H, Korganow AS, Soulas-Sprauel P (2017) Identification of autoreactive B cells labeled with nucleosome. Sci. Rep. 4, 602.

Gottenberg JE, Courvoisier DS, Hernandez MV, Iannone F, Lie E, Canhão H, Pavelka K, Hetland ML, Turesson C, Mariette X, Finckh A (2016) Brief Report : Association of Rheumatoid Factor and Anti-Citrullinated Protein Antibody Positivity With Better Effectiveness of Abatacept : Results From the Pan-European Registry Analysis. Arthritis Rheumatol. 68, 1346-1352.

Salmon JH, Gottenberg JE, Ravaud P, Cantagrel A, Combe B, Flipo RM, Schaeverbeke T, Houvenagel E, Gaudin P, Loeuille D, Rist S, Dougados M, Sibilia J, Le Loët X, Meyer O, Solau-Gervais E, Marcelli C, Bardin T, Pane I, Baron G, Perrodeau E, Mariette X ; all the investigators of the ORA registry and the French Society of Rheumatology (2016) Predictive risk factors of serious infections in patients with rheumatoid arthritis treated with abatacept in common practice : results from the Orencia and Rheumatoid Arthritis (ORA) registry. Ann Rheum Dis. 75, 1108-1113.

Alsaleh G, Nehmar R, Blüml S, Schleiss C, Ostermann E, Dillenseger JP, Sayeh A, Choquet P, Dembele D, Francois A, Salmon JH, Paul N, Schabbauer G, Bierry G, Meyer A, Gottenberg JE, Haas G, Pfeffer S, Vallat L, Sibilia J, Bahram S, Georgel P. ( 2016) Reduced DICER1 expression bestows rheumatoid arthritis synoviocytes proinflammatory properties and resistance to apoptotic stimuli. Arthritis Rheumatol. 68, 1839-1848.

Foillard S, Russier J, Seifert C, Dumortier H, Doris E (2016) Carbon nanotube-mediated delivery of budesonide to macrophages. RSC Adv. 6, 53282-53287.

Sawaf M, Dumortier H, Monneaux F (2016) Follicular helper T cells in systemic lupus erythematosus : why should they be considered as interesting therapeutic targets ? J. Immunol. Res. 2016:5767106.

Colombel S, Van Hijfte N, Poisson T, Pannecoucke X, Monneaux F*, Leclerc E* (2015) Synthesis and immunological evaluation of fluorinated a−C−galactosylceramide analogs. J. Fluorine Chem. 173, 84−91.* Corresponding author.

Salmon JH, Cacoub P, Combe B, Sibilia J, Pallot-Prades B, Fain O, Cantagrel A, Dougados M, Andres E, Meyer O, Carli P, Pertuiset E, Pane I, Maurier F, Ravaud P, Mariette X, Gottenberg JE (2015) Late-onset neutropenia after treatment with rituximab for rheumatoid arthritis and other autoimmune diseases : data from the AutoImmunity and Rituximab registry. RMD Open. 30:e000034.

Jacquemin C, Schmitt N, Contin-Bordes C, Liu Y, Narayanan P, Seneschal J, Maurouard T, Dougall D, Davizon ES, Dumortier H, Douchet I, Raffray L, Richez C, Lazaro E, Duffau P, Truchetet ME, Khoryati L, Mercié P, Couzi L, Merville P, Schaeverbeke T, Viallard JF, Pellegrin JL, Moreau JF, Muller S, Zurawski S, Coffman RL, Pascual V, Ueno H, Blanco P (2015) OX40 Ligand contributes to human lupus pathogenesis by promoting T follicular helper response. Immunity 42, 1159-1170.

Dumortier H (2013) When carbon nanotubes encounter the immune system : desired and undesired effects. Adv. Drug Deliv. Rev. 65, 2120-2126. Revue sur invitation.

Lacotte S, Décossas M, Le Coz C, Brun S, Muller S, Dumortier H (2013) Early Differentiated CD138highMHCII+IgG+ Plasma Cells Express CXCR3 and Localize into Inflamed Kidneys of Lupus Mice. PLoS One 8, e58140.

Le Coz C, Joublin A, Pasquali J-L, Korganow A-S, Dumortier H, Monneaux F (2013) Circulating TFH subset distribution is strongly affected in lupus patients with an active disease. PLoS One 8, e75319.

Russier J, Treossi E, Scarsi A, Perrozzi F, Dumortier H, Ottaviano L, Meneghetti M, Palermo V, Bianco A (2013) Evidencing the mask effect of graphene oxide : a comparative study on primary human and murine phagocytic cells. Nanoscale 5, 11234-11247.

Thomann J-S, Monneaux F, Creusat G, Spanedda M-V, Heurtault B, Habermacher C, Schuber F, Bourel-Bonnet L, Frisch B (2012) Novel glycolipid TLR2 ligands of the type Pam2Cys-α-Gal : synthesis and biological properties. Eur. J. Med. Chem. 51, 174-183.

Lacerda L, Russier J, Pastorin G, Herrero MA, Venturelli E, Dumortier H, Al-Jamal KT, Prato M, Kostarelos K, Bianco A (2012) Translocation mechanisms of chemically functionalised carbon nanotubes across plasma membranes. Biomaterials 33, 3334-43.

Lamanna G, Russier J, Dumortier H, Bianco A (2012) Enhancement of anti-inflammatory drug activity by multivalent adamantane-based dendrons. Biomaterials 33, 5610-5617.

Kéravis T*, Monneaux F*, Youbgare I, Gazi L, Bourguignon J-J, Muller S, Lugnier C (2012) Disease progression in MRL/lpr lupus-prone mice is reduced by NCS 613, a specific PDE4 inhibitor. Plos One 7, e28899. * equal contribution.

Dumortier H, Monneaux F (2012) Interleukin-21 in Systemic Lupus Erythematosus : pathogenic relevance and therapeutic applications. In : Autoimmune disorders : symptoms, diagnosis and treatment (Chapter 6) (Marquez TD & Neto DU Eds), Nova Science Publishers, New York, p145-160.

Blanchet A, Martinez A, Guillarme S, Parietti V, Monneaux F, Hénon E, Renault J-H, Nuzillard J-M, Haudrechy A (2011) Use of NEO strategy (nucleophilic addition/epoxide openning) for the synthesis of a new C-galactoside ester analogue of KRN7000. Bioorg. Med. Chem. Lett. 15, 2510-2514.

Blanchet-Cadeddu A, Hénon E, Dauchez M, Renault J-H, Monneaux F, Haudrechy A (2011) The stimulating adventure of KRN 7000. Org. Biomol. Chem. 7, 3080-3104. IF=3.559

Gaillard C, Duval M, Dumortier H, Bianco A (2011) Carbon nanotube-coupled cell adhesion peptides are non-immunogenic : a promising step toward new biomedical devices. J. Pept. Sci. 17, 139-142.

Delogu LG, Venturelli E, Manetti R, Pinna GA, Carru C, Madeddu R, Murgia L, Sgarrella F, Dumortier H, Bianco A (2011) Ex vivo impact of functionalized carbon nanotubes on human immune cells. Nanomedicine (Lond.) 7, 231-243.