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Accueil du site > Axes de recherche > Immunorégulation de la réponse B & Lupus (H. Dumortier)

B cell response immunoregulation & lupus (H. Dumortier)

Our research program is centered on the regulation of B cell responses in lupus, both in a spontaneous mouse model and in lupus patients. Our goals are :

  • Characterizing the molecular and cellular factors, which are involved in the physiopathological regulation of B cell responses during lupus
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  • Developing an innovative therapeutic strategy, based on the targeted regulation of autoreactive B cells
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The development of this project relies on the use of varied technical approaches, such as cell culture, cell sorting, flow cytometry, microscopy, biochemistry and molecular biology.